Harnessing the Power of p53 to Treat Cancer
p53 mutations are found in approximately half of all human cancers.
p53 is activated in response to DNA damage. Mutated p53 proteins lose their wild-type, or normal, tumor suppressing function.
Over 40 years of p53 experience
PMV takes a unique approach to restoring mutated p53; structurally correcting the precise geometry of the protein, hence, restoring its tumor suppressing function.
Working at PMV
At PMV we are inspired by the deep experience, diversity, and commitment of our employees. We encourage our teams to think boldly and to execute seamlessly to help conquer cancer.