Harnessing the Power of p53 to Treat Cancer

p53 mutations are found in approximately half of all human cancers.

p53 is activated in response to DNA damage. Mutated p53 proteins lose their wild-type, or normal, tumor suppressing function.

Learn more about the Science of p53

Over 40 years of p53 experience

PMV takes a unique approach to restoring mutated p53; structurally correcting the precise geometry of the protein, hence, restoring its tumor suppressing function.

Our Pipeline       Our Clinical Trials

Working at PMV

At PMV we are inspired by the deep experience, diversity, and commitment of our employees.  We encourage our teams to think boldly and to execute seamlessly to help conquer cancer.

Life at PMV