Job Opportunities

Clinical Trial Manager, Study Start-Up and Site Collaborations

Job Description: The Clinical Trial Manager, Study Start-Up and Site Collaborations will be responsible for the management and oversight of the site activation process and patient recruitment and retention goals and initiatives for oncology focused PMV Sponsored clinical studies. This key role will also operationally support Investigator Sponsored Trials (ISTs) and our Expanded Access Program (EAP). This role’s priority is to enhance accrual and increase efficiencies in site start-up, to improve site/investigator collaboration in PMV Sponsored studies, and to maintain excellence in trial execution.

Key Responsibilities

  • Serve as main point of contact internally and with sites for study start-up activities. Manage and/or oversee start-up activities for efficient and expeditious site activations. 
  • Create operational alignment that results in reduced study start-up timelines.
  • Lead, plan, and execute patient enrollment initiatives (e.g. Just-in-Time site networks, patient referral programs, patient identification through site data assets, etc.).
  • Establish and measure KPIs to oversee study start-up and patient enrollment milestones and deliverables of all site collaboration efforts. Align stakeholders and report KPI metrics to leadership.
  • Propose innovative solutions and contingency plans to site activation and patient recruitment challenges and risks.
  • Consult with Clinical Development and Operations leadership on new operational models, vendors, and strategies that may positively impact site start-up, site collaborations, patient recruitment and retention. 
  • Secure new and expand designated site network collaborations and other site programs to improve trial accruals and execution. 
  • Participate in site/ investigator engagement plans in collaboration with Medical Affairs to support site education about mechanism of disease, compound, and clinical trial.
  • Serve as Clinical Trial Manager for PMV supported ISTs and EAPs and support the creation of respective SOPs.
  • Participate in the selection and oversight of clinical vendors and contractors related to study start-up and patient recruitment and retention.
  • Serve as point of contact for Medical Science Liaisons and for site network organizations, as applicable.


  • Ability to travel up to 25%
  • Bachelor or Master of Science degree life science discipline required
  • At least 5 years of experience in clinical research
  • Understanding of all aspects of clinical drug development with particular emphasis on trial set-up, execution, and monitoring required
  • Oncology clinical trial experience required 
  • Site experience required, particularly experience in leading and/or managing aspects of clinical study start-up at an oncology investigative site 
  • Capable of leading in a matrix environment, without direct reports

How to Apply

To apply, please submit your cover letter and resume to or apply through our Online Portal.


PMV Pharmaceuticals is an Equal Opportunity Employer and all applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.